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Cytotoxic effects of ultra-diluted remedies on breast cancer cells.
Frenkel M, Mishra BM, Sen S, Yang P, Pawlus A, Vence L, Leblanc A, Cohen L, Banerji P, Banerji P.
Integrative Medicine Program-Unit 145, Department of Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030-4009, USA. frenkelm@netvision.net.il
The use of ultra-diluted natural products in the management of disease and treatment of cancer has generated a lot of interest and controversy. We conducted an in vitro study to determine if products prescribed by a clinic in India have any effect on breast cancer cell lines. We studied four ultra-diluted remedies (Carcinosin, Phytolacca, Conium and Thuja) against two human breast adenocarcinoma cell lines (MCF-7 and MDA-MB-231) and a cell line derived from immortalized normal human mammary epithelial cells (HMLE). The remedies exerted preferential cytotoxic effects against the two breast cancer cell lines, causing cell cycle delay/arrest and apoptosis . These effects were accompanied by altered expression of the cell cycle regulatory proteins, including downregulation of phosphorylated Rb and upregulation of the CDK inhibitor p27, which were likely responsible for the cell cycle delay/arrest as well as induction of the apoptotic cascade that manifested in the activation of caspase 7 and cleavage of PARP in the treated cells. T he findings demonstrate biological activity of these natural products when presented at ultra-diluted doses. Further in-depth studies with additional cell lines and animal models are warranted to explore the clinical applicability of these agents.
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Full article published by PubMed.gove
A wonderful day for British Homeopathy - Dec 1, 2009
Here follow the immortal words of Health Minister, Mike O'Brien: ' We take the view that it is not our job to stop clinicians prescribing these medications if they feel they are appropriate .' See more here.
Striking a blow for liberty worthy of John Stuart Mill, the Honorable Minister went on to say that cutting the (NHS) funding would be "illiberal" and "a denial of personal choice". He also said there were a range of opinions amongst clinicians and scientists which could not be ignored.
This was after being grilled by the House of Commons Science and Technology Committee by a number of people opposed to homeopathy. But the Health minister hinted at the essential point: NHS homeopathy is practised by trained doctors who have to take responsibility for what they do. Thank you, Minister!
This is a wonderful day for homeopathy, medicine and freedom.
More articles to come
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